Berinert® P (human C1-esterase inhibitor concentrate)
20 U / kg body weight intravenous
For adults, children and adolescents.
Cinryze® (human C1-esterase inhibitor concentrate)
1000 U intravenous
For adults and adolescents.
Firazyr® (bradykinin B2 receptor antagonist)
30 mg in a ready-to-use syringe, subcutaneous
For adult use only.
Ruconest® (Conestat alfa)
50 U/ kg body weight intravenous
4200 U for a body weight of more than 84 kg
For adult use only.
A second dose may be required for all drugs listed above.
Attention!
Cortisone, antihistamines and adrenaline are ineffective in the treatment of HAE!
This information was compiled by:
Competency Centre for HAE in accordance with Section 116b, Department of Paediatrics and Internal Medicine, Dr W. Kreuz,
Dr E. Aygören-Pürsün, Dr I. Martinez-Saguer, Johann Wolfgang Goethe University Hospital, Frankfurt am Main
www.klinik.uni-frankfurt.de
HAE Centre Mainz, Department of Dermatology, Prof. Dr K. Bork, Dr P. Staubach-Renz, Johannes Gutenberg University Hospital, Mainz
www.hautklinik-mainz.de
Applicability of this emergency therapy recommendation: Federal Republic of Germany
Status: July 2011
More information on HAE:
www.schwellungen.de www.angioedema.de